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Article

CNIH4 regulates metabolic adaptations to exercise through β-adrenergic receptor-mediated ECM remodeling

2025-08-20

Abstract excerpt

<title>Abstract</title> <p>Exercise generates various metabolic benefits by inducing extensive metabolic remodeling in skeletal muscle and adipose tissue, which is primarily mediated by β-adrenergic receptor (β-AR) signaling. However, how β-AR trafficking and activation are coordinated across metabolic tissues remains unclear. Here, we identify Cornichon homolog 4 (CNIH4) as a key regulator of β-AR membrane local...

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Literature Corpus work
e48ed58e-74a7-5e67-963e-3080e5438f63
DOI
10.21203/rs.3.rs-7324468/v1
Open publication

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CNIH4 regulates metabolic adaptations to exercise through β-adrenergic receptor-mediated ECM remodelingDOI 10.21203/rs.3.rs-7324468/v1
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