Article

mRNA vaccines encoding variant forms of Sm-TSP-2 confer protective immunity against Schistosoma mansoni

2025-08-26

Abstract excerpt

<title>Abstract</title> <p> Despite the global burden of helminth infections, no human vaccines have yet been licensed against these parasites. This study explored the development and evaluation of mRNA vaccine candidates targeting <italic>Schistosoma mansoni</italic> tetraspanin-2 ( <italic>Sm</italic> -TSP-2), an antigen currently under evaluation as a protein vaccine. We designed constructs encoding eithe...

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Literature Corpus work: e4866e55-5f94-5b8e-ab60-c4b2dd1f403f
DOI: 10.21203/rs.3.rs-7237356/v1

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mRNA vaccines encoding variant forms of Sm-TSP-2 confer protective immunity against Schistosoma mansoniDOI 10.21203/rs.3.rs-7237356/v1Read

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