Article

A Next-Generation Human Lymphatic Filariasis Vaccine Candidate, rBmHAXT, for Clinical Development

2025-06-21

Abstract excerpt

<title>Abstract</title> <p> This study was conducted to yield a robust and scalable manufacturing process for a candidate vaccine for human lymphatic filariasis (LF) - a tropical parasitic infection transmitted by mosquitoes. In previous studies, we demonstrated that removing an affinity purification tag from the fusion protein did not affect immunogenicity or vaccine efficacy. During scaled-up production of r...

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Literature Corpus work: 42504923-b548-5242-b167-d1a153c182e3
DOI: 10.21203/rs.3.rs-6572437/v1

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