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Scalability of spheroid-derived small extracellular vesicles production in stirred systems

2024-10-17

Abstract excerpt

Small extracellular vesicle (sEV)-based therapies have gained widespread interest, but challenges persist to ensure standardization and high-scale production. Implementing upstream processes in chemically defined media in stirred-tank bioreactors (STBr) is mandatory to closely control the cell environment, and to scale-up production, but it remains a significant challenge for anchorage-dependent cells. Using a hum...

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Literature Corpus work
e45f9402-dace-5d49-97d4-8f4dc9833152
DOI
10.22541/au.172916168.82000990/v1
Open publication

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Scalability of spheroid-derived small extracellular vesicles production in stirred systemsDOI 10.22541/au.172916168.82000990/v1
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