Article

Small-scale bioreactor cultivation of HEK293-based suspension cells increases extracellular vesicle yield

2026-07-15

Abstract excerpt

<h4>Purpose</h4> Extracellular vesicles (EVs) are increasingly explored as natural vehicles for drug delivery and gene therapy approaches. However, reproducible yield and scalability of EV production still pose major challenges in the clinical translation of EV-based therapies. In this study, we sought to quantify and characterize EVs released by suspension-cultured HEK293 cells (Expi293F cells) grown in shaker f...

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Literature Corpus work: 18834660-048a-593f-8231-8edc78706acc
DOI: 10.64898/2026.07.14.738239

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