Article

ECSIT is a critical factor for controlling intestinal homeostasis and tumorigenesis through regulating the translation of YAP protein

2022-08-03

Abstract excerpt

<title>Abstract</title> <p>The intestinal epithelium is the fastest renewing tissue in mammals and its regenerative process must be tightly controlled to minimize the risk of dysfunction and tumorigenesis. The orderly expression and activation of the YAP protein is a key step in driving intestinal development and crucial for intestinal regenerative responses and homeostasis. However, the regulatory mechanisms con...

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Literature Corpus work: e4582ceb-5e20-56e6-a058-3eb5f421c13b
DOI: 10.21203/rs.3.rs-1420724/v3

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