Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular Diversity of Clinically Stable Human Kidney Allografts.

JAMA network open - 4 Jan 2021

Rychkov Dmitry, Sur Swastika, Sirota Marina, Sarwal Minnie M

Abstract excerpt

Importance: Clinical decision and immunosuppression dosing in kidney transplantation rely on transplant biopsy tissue histology even though histology has low specificity, sensitivity, and reproducibility for rejection diagnosis. The inclusion of stable allografts in mechanistic and clinical studies is vital to provide a normal, noninjured comparative group for all interrogative studies on understanding allograft...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Allografts
Share to Biopsy
Share to Datasets as Topic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression

Share to Graft Rejection

Share to Kidney Transplantation

Share to Kruppel-Like Factor 4

Share to Predictive Value of Tests

Source

Open in PubMed Open full text

Identifiers

PMID: 33492376
DOI: 10.1001/jamanetworkopen.2020.35048
PMCID: PMC7835722

Genes

AR
CD4
FOSB
KLF2
KLF4
TNFAIP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular Diversity of Clinically Stable Human Kidney Allografts.PMID 33492376Read ↗

Precision Sub-phenotyping of Histologically Stable Kidney Transplants by a Composite Molecular and Cellular Instability ScoreSemantic proximity Read ↗

Adaptive Immune Landscape of T-Cell Mediated Rejection of Human Kidney AllograftsSemantic proximity Read ↗

Discovery of cellular and genetic signatures of immune tolerance in kidney transplant recipients through single cell RNA sequencing analysis.Semantic proximity Read ↗

Distinct Molecular Processes Mediate Donor-derived Cell-free DNA Release From Kidney Transplants in Different Disease StatesSemantic proximity Read ↗

Continuous Transcriptomic Indices for Assessing the Spectrum of Kidney Transplant Rejection: International Derivation and Validation StudySemantic proximity Read ↗

RNA-sequencing of Human Kidney Allografts and Delineation of T-Cell Genes, Gene Sets, and Pathways Associated With Acute T Cell–mediated RejectionSemantic proximity Read ↗

Peripheral Blood RNA Sequencing Unravels a Differential Signature of Coding and Noncoding Genes by Types of Kidney Allograft RejectionSemantic proximity Read ↗

The Trifecta Study: Comparing Plasma Levels of Donor-derived Cell-Free DNA with the Molecular Phenotype of Kidney Transplant Biopsies.Semantic proximity Read ↗

An integrated view of molecular changes, histopathology and outcomes in kidney transplants.Semantic proximity Read ↗

Single-Cell Transcriptomics of a Human Kidney Allograft Biopsy Specimen Defines a Diverse Inflammatory ResponseSemantic proximity Read ↗

Continuous indices to assess the phenotypic spectrum of kidney transplant rejectionSemantic proximity Read ↗

The Molecular Phenotype of Kidney Transplants: Insights From the MMDx Project.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.