Back to search

Article

Perceived Hearing Symptoms Organize the Ear-Disease Comorbidity Network but Are Not a Causal Lever for Brain Health: A Triangulated Analysis

2026-08-14

Abstract excerpt

<h4>Objectives</h4> To determine whether objective audiometric hearing loss, subjective hearing difficulty, and tinnitus occupy distinct roles in the population comorbidity network (perceived hub versus audiometric sparse connection), and whether the perceptually active layer exerts an independent causal effect on brain outcomes. Design, Setting, and Participants. Cross-sectional network medicine analysis of 18,9...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
e43c3330-0a7b-5855-998d-a79176a14860
DOI
10.64898/2026.08.13.26360183
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Perceived Hearing Symptoms Organize the Ear-Disease Comorbidity Network but Are Not a Causal Lever for Brain Health: A Triangulated AnalysisDOI 10.64898/2026.08.13.26360183
A Phenome-Wide Comorbidity Atlas of Age-Related Hearing Loss, Speech-in-Noise Deficits, and Tinnitus: Distinguishing Causal Signals from Correlation.Semantic proximity
Novel Risk Loci in Tinnitus and Causal Inference With Neuropsychiatric Disorders Among Adults of European Ancestry.Semantic proximity
The Perfect Storm Framework: A Testable Multi-Hit Model Linking Connective Tissue Variance, Neurodivergence, and Gene–Environment Interaction in Complex Chronic IllnessSemantic proximity
Loneliness as a Pathway Linking Hearing Decline to Cognitive Aging: Longitudinal and Genetic EvidenceSemantic proximity
Polygenic Risk Score-Based Association Analysis Identifies Genetic Comorbidities Associated with Age-Related Hearing Difficulty in Two Independent Samples.Semantic proximity
A Sensory-Cognitive Dissociation in Listeners with Hearing Difficulties: An Exploratory Analysis Linking Tinnitus to Binaural Unmasking Deficits and Speech Complaints to MemorySemantic proximity
A comprehensive evaluation on the associations between hearing and vision impairments and risk of all-cause and cause-specific dementia: results from cohort study, meta-analysis and Mendelian randomization studySemantic proximity
IEKB: a comprehensive knowledge base for inner ear genetics integrating curated associations, cochlear interactions, Bayesian candidate prioritisation, explainable dark-gene support relations, and a scientific entity networkSemantic proximity
Regional Profiling for the Frequency, Patterns, and Factors of Hearing Loss Reveals, Geriatric Age, Noise, and Inheritance History as Major Potential PredispositionsSemantic proximity
Vestibular migraine as a vestibulo-trigeminal interface phenotype: a triangulation study across genetics, peripheral multiomics and human cell atlasesSemantic proximity
Symptom dimensions to address heterogeneity in tinnitus.Semantic proximity
A cross-domain test battery for comprehensive hearing loss characterisation using functional, physiological, and vestibular measuresSemantic proximity
Select a neighboring publication to make it the new centre.