Article

Assessing human embryonic stem cell-derived dopaminergic neuron progenitor transplants using non-invasive imaging techniques

2021-01-01

Abstract excerpt

Parkinson's disease (PD) is a neurodegenerative disease that results, in part, from the progressive loss of dopaminergic (DA) neurons in the Substantia Nigra pars compacta (SNpc). Several groups have shown that human Pluripotent Stem Cell (hPSC)- derived dopaminergic neuron Progenitor Cells (DAPCs) can generate mature DA neurons and improve motor function following intrastriatal transplantation in animal models of...

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Literature Corpus work: e432d844-77c2-5c95-aec1-7b9cf7a20690
DOI: 10.17638/03131530

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