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Advancing Parkinson’s disease treatment: cell replacement therapy with neurons derived from pluripotent stem cells

21 Jun 2024

Abstract excerpt

The motor symptoms of Parkinson's disease (PD) are caused by the progressive loss of dopamine neurons from the substantia nigra. There are currently no treatments that can slow or reverse the neurodegeneration. To restore the lost neurons, international groups have initiated clinical trials using human embryonic or induced pluripotent stem cells (PSCs) to derive dopamine neuron precursors that are used as...

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PMID: 38902932
DOI: 10.1093/stmcls/sxae042

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