Article

A cancer pharmacogenomic screen powering crowd-sourced advancement of drug combination prediction

2017-10-09

Abstract excerpt

The effectiveness of most cancer targeted therapies is short lived since tumors evolve and develop resistance. Combinations of drugs offer the potential to overcome resistance, however the number of possible combinations is vast necessitating data-driven approaches to find optimal treatments tailored to a patient’s tumor. AstraZeneca carried out 11,576 experiments on 910 drug combinations across 85 cancer cell lin...

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Literature Corpus work: e3f6cb72-1eef-5e73-b7fb-c678f3613657
DOI: 10.1101/200451

Open publication

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