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Gene clusters-based pathway enrichment analysis identifies four pan-cancer subtypes with distinct molecular and clinical features

2024-11-04

Abstract excerpt

<title>Abstract</title> <p>Background Pathways-based clustering methods have been proposed to explore tumor heterogeneity. However, such methods are currently disadvantageous in that specific pathways need to be explicitly claimed. Methods We developed the PathClustNet algorithm, a pathway-based clustering method to identify cancer subtypes. This method first detects gene clusters and identifies overrepresented...

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Literature Corpus work
e3ee5c6c-7cc7-5752-8e58-3c72dab646e1
DOI
10.21203/rs.3.rs-5114169/v1
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Gene clusters-based pathway enrichment analysis identifies four pan-cancer subtypes with distinct molecular and clinical featuresDOI 10.21203/rs.3.rs-5114169/v1
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