Identifying pathways affected by cancer mutations.

Abstract excerpt

Mutations in 15 cancers, sourced from the COSMIC Whole Genomes database, and 297 human pathways, arranged into pathway groups based on the processes they orchestrate, and sourced from the KEGG pathway database, have together been used to identify pathways affected by cancer mutations. Genes studied in ≥15, and mutated in ≥10 samples of a cancer have been considered recurrently mutated, and pathways with...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Metabolic Networks and Pathways
• Share to Models, Genetic
• Share to Mutation