Article

Novel cancer subtyping method based on patient-specific gene regulatory network

2021-03-25

Abstract excerpt

<h4>ABSTRACT</h4> The identification of cancer subtypes is important for the understanding of tumor heterogeneity. In recent years, numerous computational methods have been proposed for this problem based on the multi-omics data of patients. It is widely accepted that different cancer subtypes are induced by different molecular regulatory networks. However, only a few incorporate the differences between their mol...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 78967967-97ec-5119-9ae1-b5d4f78753cf
DOI: 10.1101/2021.03.24.436731

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Novel cancer subtyping method based on patient-specific gene regulatory networkDOI 10.1101/2021.03.24.436731Read

Constructing cancer patient-specific and group-specific gene networks with multi-omics dataSemantic proximity Read

MDICC: novel method for multi-omics data integration and cancer subtype identificationSemantic proximity Read

Network based stratification of major cancers by integrating somatic mutation and gene expression data.Semantic proximity Read

Tumor characterization and stratification by integrated molecular profiles reveals essential pan-cancer featuresSemantic proximity Read

Cancer Subtype Discovery Based on Integrative Model of Multigenomic DataSemantic proximity Read

An integrated analysis of the cancer genome atlas data discovers a hierarchical association structure across thirty three cancer typesSemantic proximity Read

CLCluster: a redundancy-reduction contrastive learning-based clustering method of cancer subtype based on multi-omics dataSemantic proximity Read

Personalized characterization of diseases using sample-specific networksSemantic proximity Read

Integrating genetic and gene expression data in network-based stratification analysis of cancersSemantic proximity Read

Generalizable transcriptome-based tumor malignant level evaluation and molecular subtyping towards precision oncology.Semantic proximity Read

Identifying Cancer Subtypes from miRNA-TF-mRNA Regulatory Networks and Expression DataSemantic proximity Read

Multi-omics cluster defines the subtypes of CRC with distinct prognosis and tumor microenvironmentSemantic proximity Read