Article

Cross-family interactions of vascular endothelial growth factors and platelet-derived growth factors on the endothelial cell surface: A computational model

2025-03-04

Abstract excerpt

Angiogenesis, the formation of new vessels from existing vessels, is mediated by vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF). Despite discoveries supporting the cross-family interactions between VEGF and PDGF families, sharing the binding partners between them makes it challenging to identify growth factors that predominantly affect angiogenesis. Systems biology offers promi...

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Literature Corpus work: 40a992e8-5e4c-5d4a-9ec4-3039750943f6
DOI: 10.1101/2025.02.27.640640

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