Article

Acquisition of cancer stem cell properties during EMT requires cell division

2021-07-02

Abstract excerpt

Cancer cells acquire stem cell and mesenchymal properties during epithelial-to-mesenchymal transition (EMT), facilitating metastasis and chemoresistance [1-6]. In this study, we find that mammary epithelial cells quickly develop mesenchymal phenotype in response to EMT-inducing signals; however, acquiring stemness takes several days and always requires a preceding mesenchymal program. In addition, we observe that...

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Literature Corpus work: e397d04c-faaa-5564-ba3d-c9d30377c23d
DOI: 10.1101/2021.07.01.449976

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