Article

Engineering a Computable Epiblast for in silico Modeling of Developmental Toxicity

2023-09-29

Abstract excerpt

Developmental hazard evaluation is an important part of assessing chemical risks during pregnancy. Toxicological outcomes from prenatal testing in pregnant animals result from complex chemical-biological interactions, and while New Approach Methods (NAMs) based on in vitro bioactivity profiles of human cells offer promising alternatives to animal testing, most of these assays lack cellular positional information,...

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Literature Corpus work: e3769133-9b79-594d-9886-0c475f362e64
DOI: 10.20944/preprints202309.2097.v1

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