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Article

Starvation protects germline stem cells and extends reproductive longevity in C. elegans.

Science (New York, N.Y.) - 13 Nov 2009

Angelo Giana, Van Gilst Marc R

Abstract excerpt

The study of starvation-resistant biological programs has elucidated numerous mechanisms influencing aging. Here we present the discovery and characterization of starvation-induced adult reproductive diapause (ARD) in Caenorhabditis elegans. ARD differs from the C. elegans dauer diapause in that it enables sexually mature adults to delay reproductive onset 15-fold and extend total adult life span at least...

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PMID: 19713489
DOI: 10.1126/science.1178343

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