Article

“Axonal Length Determines distinct homeostatic phenotypes in human iPSC derived motor neurons on a bioengineered platform”

2021-09-01

Abstract excerpt

Stem cell-based experimental platforms for neuroscience can effectively model key mechanistic aspects of human development and disease. However, conventional culture systems often overlook the engineering constraints that cells face in vivo . This is particularly relevant for neurons covering long range connections such as spinal motor neurons (MNs). The axons of these neurons extend up to 1m in length and requir...

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Literature Corpus work: e35ed914-a738-531b-8fde-3121ac66fdd0
DOI: 10.1101/2021.08.30.458271

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