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Comprehensive analysis of DNA damage repair deficiency in 10,284 pan-cancer study

1 Nov 2021

Abstract excerpt

Background: Disruption of the DNA damage repair (DDR) gene is related to cancer progression, treatment selection, and is subjected to radiation and targeted therapies with limited success. This paper conducted a comprehensive analysis to explore the distribution of DDR mutations in Chinese pan-cancer patients. Methods: A total of 10,284 consecutive cases were analyzed in 24 cancer types [non-small cell lung...

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PMID: 34988170
DOI: 10.21037/atm-21-5449

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