Article

Genomic insights into the mechanism of NK3R antagonists for treatment of menopausal vasomotor symptoms

2022-05-26

Abstract excerpt

<h4>Background</h4> Menopausal vasomotor symptoms (VMS) significantly impact women’s quality of life, and whilst hormone replacement therapy (HRT) is effective, it is not appropriate for all. We aimed to identify new drug targets for VMS and understand reasons for HRT use through genomic analyses. <h4>Methods</h4> In up to 153,152 women from UK Biobank, a population-based cohort, we performed a genome-wide associa...

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Literature Corpus work: e35226b9-9b5c-51e7-b2c4-bcb5a9df134f
DOI: 10.1101/2022.05.25.22275501

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