Article
Polymorphisms of the HTR3B gene are associated with post-surgery emesis in a Chinese Han population.
Journal of clinical pharmacy and therapeutics - 1 Apr 2013
Ma Xiao-Xu, Chen Qi-Xing, Wu Shui-Jing, Hu Yan, Fang Xiang-Ming
Abstract excerpt
WHAT IS KNOWN AND OBJECTIVES: The serotoninergic receptor 5-hydroxytryptamine (serotonin) receptor 3 (HTR3) is instrumental in the regulation of nausea and emesis (vomiting).This study investigated whether common genomic variations of the A and B subunits of HTR3 (HTR3A, HTR3B) are associated with the incidence of post-operative vomiting in a Chinese Han population. METHODS: Two hundred and thirty-one female...
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