Article

Menopausal Hormone Therapy and Risk of Neuropsychiatric Disease: A Drug Target Mendelian Randomisation Study

2024-10-17

Abstract excerpt

<title>Abstract</title> <p>The effects of menopausal hormone therapy (MHT) on neurological and psychiatric disease risk have shown conflicting results across epidemiological and clinical studies. Given the widespread propagation of MHT among females experiencing menopausal symptoms, clarifying causality and impact is critical for informed decision-making. Although randomised controlled trials can establish causal...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6c658cf9-321d-58df-b7f9-98e59da7af24
DOI: 10.21203/rs.3.rs-5252067/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Menopausal Hormone Therapy and Risk of Neuropsychiatric Disease: A Drug Target Mendelian Randomisation StudyDOI 10.21203/rs.3.rs-5252067/v1Read

Investigating the synergistic effects of hormone replacement therapy, apolipoprotein E and age on brain health in the UK Biobank.Semantic proximity Read

Age at Natural Menopause and Disease Patterns Across the Lifespan: Phenome-Wide and Genetic Evidence from Multi-Ancestry BiobanksSemantic proximity Read

Women's reproductive traits and major depressive disorder: A two-sample Mendelian randomization study.Semantic proximity Read

Women’s brain aging: effects of sex-hormone exposure, pregnancies, and genetic risk for Alzheimer’s diseaseSemantic proximity Read

Genetic evidence for causal relationships between age at natural menopause and the risk of aging-associated adverse health outcomesSemantic proximity Read

Postmortem tissue biomarkers of menopausal transitionSemantic proximity Read

Looking forward in geriatric anxiety and depression: implications of basic science for the future.Semantic proximity Read

Hormone replacement therapy and dementia risk among postmenopausal women: evidence from the UK BiobankSemantic proximity Read

Antidepressant Use and Bone Health: Evidence From Mendelian Randomisation.Semantic proximity Read

The role of sex hormones in severe mental illness: A genetic exploration.Semantic proximity Read

Women's brain aging: Effects of sex-hormone exposure, pregnancies, and genetic risk for Alzheimer's disease.Semantic proximity Read

Testosterone, sex hormone-binding globulin, insulin-like growth factor-1 and endometrial cancer risk: observational and Mendelian randomization analyses.Semantic proximity Read