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NK cell receptor repertoires evolve under increased purifying selection but are not more diverse in menstruating mammals

2026-03-06

Abstract excerpt

The immune system plays key roles in the mammalian uterine cycle, particularly for menstruation, a dramatic tissue renewal mechanism independently acquired four times in eutherians. These roles specifically involve NK cells through the expression of surface killer cell immunoglobulin-like receptors (KIRs) and killer cell lectin-like receptors (KLRs), respectively part of the immunoglobulin-like and lectin-like gen...

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Literature Corpus work
1173196d-a803-5c1a-860a-04e62f05d87e
DOI
10.64898/2026.03.05.709850
Open publication

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NK cell receptor repertoires evolve under increased purifying selection but are not more diverse in menstruating mammalsDOI 10.64898/2026.03.05.709850
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