Article

The protection of 2-D08 to sevoflurane-induced hypomyelination is mediated by Kir4.1

2025-08-29

Abstract excerpt

<h4>Background: </h4> and Purpose: The developing brain of infants and young children is in a critical period of myelination, where prolonged or repeated general anesthesia can lead to hypomyelination. However, there is currently no effective treatment, highlighting the urgent need for new therapeutic strategies. Kir4.1 plays pivotal roles in the process of myelination, besides, 2-D08 up-regulates the expression o...

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Literature Corpus work: e3320773-1555-5814-a535-6268f59124de
DOI: 10.22541/au.175648012.21652425/v1

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