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Epigenetic alterations at distal enhancers are linked to proliferation in human breast cancer

2021-04-14

Abstract excerpt

Breast cancer is a highly heterogeneous disease driven by multiple factors including genetic and epigenetic alterations. DNA methylation patterns have been shown to be altered on a genome-wide scale and previous studies have highlighted the critical role of aberrant DNA methylation on gene expression and breast cancer pathogenesis. Here, we perform genome-wide expression-methylation Quantitative Trait Loci (emQTL)...

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Literature Corpus work
e2ce289e-22d0-5b58-bb46-647d996a3bc3
DOI
10.1101/2021.04.14.439799
Open publication

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Epigenetic alterations at distal enhancers are linked to proliferation in human breast cancerDOI 10.1101/2021.04.14.439799
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