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Transgenerational inheritance of abnormal spermatogenesis with <i>Igf2/H19</i> epigenetic alteration in CD1 mouse induced by <i>in utero</i> arsenic exposure

2020-04-18

Abstract excerpt

Developmental exposure to environmental toxicants can induce transgenerational reproductive disease phenotypes through epigenetic mechanisms. However, little is known about the transgenerational effects of arsenic exposure. We hypothesize that prenatal arsenic exposure may result in impaired spermatogenesis in subsequent generations of male mice. To test our hypothesis, we treated pregnant CD-1 (F0) mice with drin...

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Literature Corpus work
e291bb53-f415-590c-8818-35cf84c4e565
DOI
10.1101/2020.04.16.044032
Open publication

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Transgenerational inheritance of abnormal spermatogenesis with <i>Igf2/H19</i> epigenetic alteration in CD1 mouse induced by <i>in utero</i> arsenic exposureDOI 10.1101/2020.04.16.044032
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