Article

Environmentally-relevant doses of bisphenol A and S exposure in utero disrupt germ cell programming across generations resolved by single nucleus multi-omics

2024-12-10

Abstract excerpt

<h4>Background</h4> Exposure to endocrine-disrupting chemicals (EDCs), such as bisphenol A (BPA), disrupts reproduction across generations. Germ cell epigenetic alterations are proposed to bridge transgenerational reproductive defects resulting from EDCs. Previously, we have shown that prenatal exposure to environmentally relevant doses of BPA or its substitute, BPS, caused transgenerationally maintained reproduc...

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Literature Corpus work: 13b0d3db-c8ba-5d9a-9f19-1640485c0c6a
DOI: 10.1101/2024.12.05.627072

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