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Article

Gestational arsenic exposure and paternal intergenerational epigenetic inheritance.

Toxicology and applied pharmacology - 15 Dec 2020

Nohara Keiko, Suzuki Takehiro, Okamura Kazuyuki

Abstract excerpt

A growing body of evidence has shown that gestational exposure to environmental factors such as imbalanced diet, environmental chemicals, and stress can lead to late-onset health effects in offspring and that some of these effects are heritable by the next generation and subsequent generations. Furthermore, altered epigenetic modifications in DNA methylation, histone modifications and small RNAs in a single sperm...

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PMID: 33160984
DOI: 10.1016/j.taap.2020.115319

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