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Article

Dioxin (TCDD) Induces Epigenetic Transgenerational Inheritance of Adult Onset Disease and Sperm Epimutations

26 Sept 2012

Abstract excerpt

Environmental compounds can promote epigenetic transgenerational inheritance of adult-onset disease in subsequent generations following ancestral exposure during fetal gonadal sex determination. The current study examined the ability of dioxin (2,3,7,8-tetrachlorodibenzo[p]dioxin, TCDD) to promote epigenetic transgenerational inheritance of disease and DNA methylation epimutations in sperm. Gestating F0...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23049995
DOI: 10.1371/journal.pone.0046249

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