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A 5-repurposed drug candidates identified in motor neurons and muscle tissues with amyotrophic lateral sclerosis by network biology and machine learning based on gene expression

2024-11-15

Abstract excerpt

not-yet-known not-yet-known not-yet-known unknown Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder that leads to motor neuron degeneration, muscle weakness, and respiratory failure. Despite ongoing research, effective treatments for ALS are limited. This study aimed to apply network biology and machine learning (ML) techniques to identify novel repurposed drug candidates for ALS....

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Literature Corpus work
392d6858-d0b5-5ad0-bed8-32af1842d532
DOI
10.22541/au.173164879.96501791/v1
Open publication

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