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Integrated gene-based and pathway analyses using UK Biobank data identify novel genes for chronic respiratory diseases.

Gene - 30 Jan 2021

Wang Lijuan, Fang Rui, Zhu Meng, Qin Na, Wang Yuzhuo, Fan Jingyi, Sun Qi, Ji Mengmeng, Fan Xikang, Xie Junxing, Ma Hongxia, Dai Juncheng

Abstract excerpt

BACKGROUND: Chronic respiratory diseases have become a non-negligible cause of death globally. Although smoking and environmental exposures are primary risk factors for chronic respiratory diseases, genetic factors also play an important role in determining individual's susceptibility to diseases. Here we performed integrated gene-based and pathway analyses to systematically illuminate the heritable...

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Identifiers

PMID: 33181258
DOI: 10.1016/j.gene.2020.145287

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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