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Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19

11 Aug 2021

Abstract excerpt

In COVID-19, immune responses are key in determining disease severity. However, cellular mechanisms at the onset of inflammatory lung injury in SARS-CoV-2 infection, particularly involving endothelial cells, remain ill-defined. Using Syrian hamsters as a model for moderate COVID-19, we conduct a detailed longitudinal analysis of systemic and pulmonary cellular responses, and corroborate it with datasets from...

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PMID: 34381043
DOI: 10.1038/s41467-021-25030-7

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