Article

Tumor Mutational Burden is Associated with Poor Outcomes in Diffuse Glioma.

2020-02-11

Abstract excerpt

<h4>Background: </h4> Tumor mutational burden (TMB) is a potential biomarker for immune checkpoint therapy and prognosis. The impact of TMB on clinical outcomes and the correlation coefficient between exome sequencing and targeted sequencing in glioma have not yet been explored. <h4>Methods:</h4> Somatic mutations in the coding regions of 897 primary gliomas and the clinical and RNA-seq data of 654 patients in The...

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Literature Corpus work: e217075d-4d55-5396-956f-4b6fed8023d1
DOI: 10.21203/rs.2.11924/v4

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