Article

Association Between Tumor Mutation Burden and Prognosis in Lower-Grade Glioma: An Exploratory Study 

2021-01-14

Abstract excerpt

<h4>Background: </h4> The therapeutic efficacy of immune checkpoint inhibitor therapy is highly influenced by tumor mutation burden (TMB). The relationship between TMB and prognosis in lower-grade glioma is still unclear. We aimed to explore the relationships and mechanisms between them in lower-grade glioma. <h4>Methods: </h4>: We leveraged somatic mutation data from The Cancer Genome Atlas (TCGA). Clinical cases...

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Literature Corpus work: 72c2648b-76b1-551d-af84-ccd4d011e766
DOI: 10.21203/rs.3.rs-137165/v1

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