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The circular RNA Ataxia-telangiectasia mutated ( <i>cATM</i> ) regulates oxidative stress in smooth muscle cells in expanding abdominal aortic aneurysms

2022-11-11

Abstract excerpt

<h4>ABSTRACT</h4> An abdominal aortic aneurysm (AAA) is a pathological widening of the aortic wall characterized by loss of smooth muscle cells (SMCs), extracellular matrix degradation, and local inflammation. This condition is often asymptomatic until rupture occurs, leading to high morbidity and mortality rates. Diagnosis is often accidental, and for now, the only available treatment option remains surgical int...

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Literature Corpus work: e2050ced-3b03-5f3c-81e4-227b3162d2a6
DOI: 10.1101/2022.11.11.516115

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