Construction of a circRNA - Mediated ceRNA Network Reveals Novel Biomarkers for Aortic Dissection

Abstract excerpt

<h4>Background: </h4> Aortic dissection (AD) is a rare and lethal disorder with its genetic basis remains largely unknown. Many studies have confirmed that circular RNAs (circRNAs) play important roles in various physiological and pathological processes. However, the roles of circRNAs in AD are still unclear and need further investigation. The present study aimed to elucidate the underlying molecular mechanisms of...

Topics

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• Aortic Aneurysm
• Aortic Disease and Treatment Approaches
• Aortic Dissection
• Cardiac Valve Diseases and Treatments
• Cell Movement
• Circular RNAs in diseases
• Gene Regulatory Networks
• MicroRNAs

Identifiers and source

Literature Corpus work

a5f756a9-29ca-574f-8552-6740d4335c6b

DOI

10.21203/rs.3.rs-1059642/v1