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HER2-targeting CAR-T cells show highly efficient anti-tumor activity against glioblastoma both in vitro and in vivo

2024-02-13

Abstract excerpt

<title>Abstract</title> <p>Glioblastoma (GBM) is the most common and aggressive malignant brain tumor in adults. Current treatment options for GBM include surgical resection, radiation, and chemotherapy, which predominantly only slow cancer growth and reduce symptoms, resulting in a 5-year survival rate of no more than 10%. Chimeric antigen receptor (CAR)-T cell therapy is a new class of cellular immunotherapies...

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Literature Corpus work
e1dbda9d-3746-5800-8fba-a0d3dcc9e87a
DOI
10.21203/rs.3.rs-3926646/v1
Open publication

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HER2-targeting CAR-T cells show highly efficient anti-tumor activity against glioblastoma both in vitro and in vivoDOI 10.21203/rs.3.rs-3926646/v1
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