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Human Endometrial Transcriptome and Progesterone Receptor Cistrome Reveal Important Pathways and Epithelial Regulators

29 Oct 2019

Abstract excerpt

CONTEXT: Poor uterine receptivity is one major factor leading to pregnancy loss and infertility. Understanding the molecular events governing successful implantation is hence critical in combating infertility. OBJECTIVE: To define Progesterone Receptor (PGR)-regulated molecular mechanisms and epithelial roles in receptivity. DESIGN: RNA-sequencing and PGR-ChIP-seq were conducted in parallel to identify...

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PMID: 31665330
DOI: 10.1210/clinem/dgz117

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