Article

Dynamic chromatin remodeling in cycling human endometrium at single cell level

2023-06-05

Abstract excerpt

<h4>SUMMARY</h4> Estrogen-dependent proliferation followed by progesterone-dependent differentiation of the endometrium culminates in a short implantation window. We performed single cell ATAC-seq on endometrial samples obtained across the menstrual cycle to investigate the regulation of temporal gene networks that control embryo implantation. We identified uniquely accessible chromatin regions in all major cellu...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 699bf7a2-accc-5f56-a26e-9d7e86d2cc76
DOI: 10.1101/2023.06.01.543328

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Dynamic chromatin remodeling in cycling human endometrium at single cell levelDOI 10.1101/2023.06.01.543328Read

Dynamic chromatin remodeling in cycling human endometrium at single-cell levelSemantic proximity Read

Analysis of chromatin accessibility in decidualizing human endometrial stromal cellsSemantic proximity Read

Single cell RNAseq provides a molecular and cellular cartography of changes to the human endometrium through the menstrual cycleSemantic proximity Read

CORE CONSERVED TRANSCRIPTIONAL REGULATORY NETWORKS DEFINE THE INVASIVE TROPHOBLAST CELL LINEAGESemantic proximity Read

Reciprocal Changes of H3K27Ac and H3K27me3 at the Promoter Regions of the Critical Genes for Endometrial DecidualizationSemantic proximity Read

Transcriptomic Analysis of Human Endometrium Stromal Cells During Early Embryo Implantation (Within 48 Hour) in VitroSemantic proximity Read

An integrated single-cell reference atlas of the human endometriumSemantic proximity Read

Global alterations of the epigenetic landscape define endometrial receptivity and provide a hallmark for endometriosisSemantic proximity Read

Steroid hormones regulate genome-wide epigenetic programming and gene transcription in human endometrial cells with marked aberrancies in endometriosisSemantic proximity Read

Active remodeling of the chromatin landscape directs extravillous trophoblast cell lineage developmentSemantic proximity Read

Human Endometrial Transcriptome and Progesterone Receptor Cistrome Reveal Important Pathways and Epithelial RegulatorsSemantic proximity Read

An integrated single-cell reference atlas of the human endometriumSemantic proximity Read