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The impact of telomere length on prostate cancer aggressiveness, genomic instability and health disparities

2023-12-02

Abstract excerpt

The telomere repetitive TTAGGG motif at the ends of chromosomes, serves to preserve genomic integrity and chromosomal stability. In turn, genomic instability is a hallmark of cancer - implicating telomere disturbance. Prostate cancer (PCa) shows significant ancestral disparities, with men of African ancestry at the greatest risk for aggressive disease and associated genomic instability. Yet, no study has explored...

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Literature Corpus work
e1b8e485-9d30-5e5b-b871-6c1e26df1fb7
DOI
10.21203/rs.3.rs-3534553/v1
Open publication

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