Article

The Telomere Length Landscape of Prostate Cancer

2021-05-25

Abstract excerpt

Replicative immortality is a hallmark of cancer, and can be achieved through telomere lengthening and maintenance. We report telomere lengths (TLs) of 392 localized prostate cancer tumours and characterize their relationship to genomic, transcriptomic and proteomic features. Shorter tumour TLs were associated with elevated genomic instability, including single-nucleotide variants, indels and structural variants. G...

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Literature Corpus work: 8f4eeb72-4fc2-5bc1-8af7-6dd226ad6ea9
DOI: 10.1101/2021.05.22.445239

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