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Genetic and epigenetic alterations of colorectal cancer

1 Jan 2018

Abstract excerpt

Colorectal cancer (CRC) arise from multi-step carcinogenesis due to genetic mutations and epigenetic modifications of human genome. Genetic mutations and epigenetic modifications were originally established as 2 independent mechanisms contributing to colorectal carcinogenesis. However, recent evidences demonstrate that there are interactions between these 2 mechanisms. Genetic mutations enable disruption of...

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Identifiers

PMID: 30090031
DOI: 10.5217/ir.2018.16.3.327

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