Article

Decoding G0 somatic mutants through deep phenotyping and mosaic pattern analysis in the zebrafish skeleton

2018-11-08

Abstract excerpt

<h4>ABSTRACT</h4> Genetic mosaicism manifests as spatially variable phenotypes, whose detection and interpretation remains challenging. This study identifies biological factors influencing spatial phenotypic patterns in the skeletons of somatic mutant zebrafish, and tests methods for their analysis using deep phenotyping. We explore characteristics of loss-of-function clusters in the skeleton of CRISPR-edited G0...

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Literature Corpus work: e18df36d-7b10-5f3e-b294-dd799d2b7c88
DOI: 10.1101/466185

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