Article

Global Burden of Periodontitis and Causal Links with Sleep Disorders: A Mendelian Randomization and Multi-Omics Analysis with Focus on Lactylation-Mediated Mechanisms

2025-11-11

Abstract excerpt

<title>Abstract</title> <p>Background Periodontitis and insomnia represent two prevalent chronic conditions with substantial global health impact. Emerging evidence suggests potential bidirectional relationships between these conditions, yet causal mechanisms remain poorly understood. Methods We conducted a comprehensive three-pronged analysis using Global Burden of Disease (GBD) 2021 data to quantify periodontit...

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Literature Corpus work: e1852600-9b2e-59d8-abf0-f6cb0abb2e5f
DOI: 10.21203/rs.3.rs-7547880/v1

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