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Article

Chronic periodontitis and respiratory diseases: A bidirectional two-sample Mendelian randomization study.

Medicine - 16 Jan 2026

Ye Hong, Chen Yiru, Lyv Jingzhe, Fang Qian, Cai Zhihao, Zhong Liangjun

Abstract excerpt

Evidence from observational research suggests potential links between chronic periodontitis (CP) and respiratory diseases, but these associations remain susceptible to residual confounding and reverse causation. This study aimed to evaluate whether CP exerts a direct causal influence on chronic obstructive pulmonary disease, asthma, or pneumonia and whether these respiratory diseases in turn affect the risk of...

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Asthma
Chronic Periodontitis
CP gene
Genome-Wide Association Study
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Pulmonary Disease, Chronic Obstructive

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Open in PubMed Open full text

Identifiers

PMID: 41560027
DOI: 10.1097/MD.0000000000046977
PMCID: PMC12826142

Genes

CP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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