Article

Developmental sex-specific transcriptomic patterns can be altered by transgenic expression of Uty

2023-05-22

Abstract excerpt

The genetic material encoded on X and Y chromosomes provides the foundation by which biological sex differences are established. Epigenetic regulators expressed on these sex chromosomes, including Kdm6a ( Utx ), Kdm5c , and Ddx3x have far-reaching impacts on transcriptional control of phenotypic sex differences. Although the functionality of UTY (Kdm6c , the Y-linked homologue of UTX), has been supported by more r...

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Literature Corpus work: e14f3394-fb6e-542d-a456-4a86052ba605
DOI: 10.21203/rs.3.rs-2928137/v1

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