Article

Correlation analysis of RasGRP4 gene expression with mast cell infiltration and clinical prognosis of lung adenocarcinoma

2025-12-17

Abstract excerpt

<title>Abstract</title> <p> <bold>Objective</bold> To explore the correlation between Ras guanyl nucleotide releasing protein 4 (RasGRP4) expression in lung adenocarcinoma (LUAD) and mast cells (MCs) infiltration, as well as its impact on clinical prognosis. <bold>Methods</bold> 1. The Cancer Genome Atlas (TCGA) database was utilized to analyze RasGRP4 expression in LUAD tissues and to assess its potential as...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e1373873-933d-5f4f-a0a8-345b2f823bc6
DOI: 10.21203/rs.3.rs-8318061/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Correlation analysis of RasGRP4 gene expression with mast cell infiltration and clinical prognosis of lung adenocarcinomaDOI 10.21203/rs.3.rs-8318061/v1Read

RASGRP2 is a potential immune-related biomarker and regulates mitochondrial-dependent apoptosis in lung adenocarcinomaSemantic proximity Read

Clinical Significance and Regulatory Network of Mast Cells in Early-Stage Lung AdenocarcinomaSemantic proximity Read

ANKRD1 Facilitates Tumor Progression and Immune Evasion in Stomach Adenocarcinoma through STAT3 Activation and Remodeling of the Tumor MicroenvironmentSemantic proximity Read

GPR37 promotes the malignancy of lung adenocarcinoma via TGF-β/Smad pathwaySemantic proximity Read

GRPR Drives Metastasis via CRABP2 and FNDC4 Pathways in Lung AdenocarcinomaSemantic proximity Read

Prognostic value and immunological role of NDRG1 gene in pan-cancerSemantic proximity Read

The Diacylglycerol-dependent translocation of ras guanine nucleotide-releasing protein 4 inside a human mast cell line results in substantial phenotypic changes, including expression of interleukin 13 receptor alpha2.Semantic proximity Read

Bioinformatics analysis of immune cell infiltration, immune-related genes, and signaling pathways in the blood of allergic rhinitis patientsSemantic proximity Read

Function of RasGRP3 in the formation and progression of human breast cancerSemantic proximity Read

Dysregulated RASGRP1 expression through RUNX1 mediated transcription promotes autoimmunitySemantic proximity Read

Analysis of the Expression and Clinical Significance of VIPR1 in Lung Adenocarcinoma Based on TCGA DatabaseSemantic proximity Read