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Article

Function of RasGRP3 in the formation and progression of human breast cancer

29 Apr 2014

Abstract excerpt

INTRODUCTION: Ras guanine nucleotide exchange factors (RasGEFs) mediate the activation of the Ras signaling pathway that is over activated in many human cancers. The RasGRP3, an activator of H-Ras and R-Ras protein exerts oncogenic effects and the overexpression of the protein is observed in numerous malignant cancer types. Here, we investigated the putative alteration of expression and potential function of...

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Share to Cancer, Stress, Anesthesia, and Immune Response
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PMID: 24779681
DOI: 10.1186/1476-4598-13-96

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