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GRPR Drives Metastasis via CRABP2 and FNDC4 Pathways in Lung Adenocarcinoma

23 Dec 2024

Abstract excerpt

Metastasis is a leading cause of lung adenocarcinoma (LUAD)-related mortality and presents significant challenges for treatment. The gastrin-releasing peptide receptor (GRPR), a member of the G protein-coupled receptor (GPCR) family, has an unclear role in LUAD progression. This study aimed to investigate the function and underlying mechanisms of GRPR in LUAD metastasis. Our findings revealed that GRPR levels...

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PMID: 39768218
DOI: 10.3390/cells13242128

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